Description

1-(3-Chlorophenyl)-3-[3-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Urea is a high-purity, synthetic organic compound featuring a urea core functionalized with chlorophenyl and boronic ester groups. This molecular structure makes it a valuable key intermediate or building block in advanced chemical synthesis, particularly in pharmaceutical research and materials science. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially in kinase inhibitor and other targeted therapy research.
• Suzuki-Miyaura Cross-Coupling Reactions: The tetramethyl-1,3,2-dioxaborolan-2-yl (pinacol boronic ester) group enables efficient carbon-carbon bond formation, a cornerstone of modern medicinal chemistry.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides where the urea and aryl chloride motifs are pharmacologically relevant.
• Organic Electronic Materials: Potential precursor for the synthesis of organic semiconductors or charge-transport materials due to its conjugated aromatic system.
• Chemical Biology Probes: Can be utilized in the design of molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	1-(3-Chlorophenyl)-3-[3-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Urea
CAS No.	874302-01-9
Molecular Formula	C19H22BClN2O3
Molecular Weight	372.65 g/mol
Synonyms	1-(3-Chlorophenyl)-3-[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]urea; N-(3-Chlorophenyl)-N'-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]urea; 3-Chlorophenyl-[3-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-urea; Urea, N-(3-chlorophenyl)-N'-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-; B-[3-[[(3-Chlorophenyl)amino]carbonyl]amino]phenyl]boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 1-(3-Chlorophenyl)-3-[3-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Urea is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed specifications are provided for each lot, supporting traceability and compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. The compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.