Description

1-(4-Chlorophenyl)-3-[3-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Urea is a specialized boronic ester derivative that serves as a critical synthetic intermediate. This compound is valued for its role in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. It is primarily needed by pharmaceutical research and development teams and advanced material scientists working on novel organic electronic compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biphenyl or substituted phenyl moieties.
• Suzuki-Miyaura Cross-Coupling Reagent: Provides the boronate ester component for palladium-catalyzed carbon-carbon bond formation, essential for creating complex organic molecules.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that require specific aryl-aryl linkages.
• Material Science & OLED Development: Serves as a precursor for organic light-emitting diode (OLED) materials and other advanced organic electronic components.
• Ligand Synthesis: Intermediate for the preparation of specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying biological processes and protein interactions.

Basic Information

Product Name	1-(4-Chlorophenyl)-3-[3-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Urea
CAS No.	874302-00-8
Molecular Formula	C19H22BClN2O3
Molecular Weight	372.65 g/mol
Synonyms	N-(4-Chlorophenyl)-N'-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]urea; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl(4-chlorophenyl)urea; Urea, N-(4-chlorophenyl)-N'-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-; 1-(4-Chlorophenyl)-3-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]urea; Boric acid ester urea derivative; Boronate ester urea intermediate
EINECS	Contact for details

Quality Control

Our 1-(4-Chlorophenyl)-3-[3-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Urea is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. All materials are characterized by NMR (1H, 13C, 11B), HPLC, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and easily oxidized; for long-term storage, it is recommended to keep the container under an inert atmosphere (argon or nitrogen) in a desiccator.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.