Description

Methyl 3-Amino-5-Chloro-2-Nitrobenzoate is a high-purity, multi-functional chemical intermediate essential for advanced organic synthesis. Its unique structure, featuring both amino and nitro substituents on a chlorinated benzoate core, makes it a valuable building block for creating complex molecules. This compound is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors. It serves as a critical precursor in the synthesis of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key starting material for the synthesis of complex drug candidates, particularly those with benzodiazepine or quinazoline backbones.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its halogenated aromatic structure.
• Dye and Pigment Manufacturing: Serves as a precursor for azo dyes and other high-performance colorants due to its reactive amino and nitro groups.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and photoactive polymers.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) for creating novel carbon-nitrogen bonds.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and exploring new synthetic pathways.

Basic Information

Product Name	Methyl 3-Amino-5-Chloro-2-Nitrobenzoate
CAS No.	874301-23-2
Molecular Formula	C8H7ClN2O4
Molecular Weight	230.61 g/mol
Synonyms	Methyl 3-Amino-5-Chloro-2-Nitrobenzoate; 3-Amino-5-Chloro-2-Nitrobenzoic Acid Methyl Ester; Benzoic acid, 3-amino-5-chloro-2-nitro-, methyl ester; Methyl 3-Amino-5-Chloro-2-Nitrobenzoate; Methyl 3-Amino-5-Chloro-2-Nitrobenzoate; 5-Chloro-2-nitro-3-aminobenzoic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 3-Amino-5-Chloro-2-Nitrobenzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.