Description

1-Cyclohexyl-3-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)phenyl)urea is a high-value, functionalized chemical intermediate featuring a protected boronic acid ester (pinacol boronate) group and a urea linkage. This compound is critical for advanced organic synthesis, particularly in cross-coupling reactions like the Suzuki-Miyaura reaction, enabling the precise construction of complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, agrochemical development, and materials science for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially for kinase inhibitors and other small-molecule therapeutics.
• Medicinal Chemistry Research: Used in high-throughput screening libraries and structure-activity relationship (SAR) studies to explore new bioactive compounds.
• Agrochemical Development: Serves as a precursor in creating novel herbicides, fungicides, and plant growth regulators.
• Material Science: Employed in the synthesis of organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Biology Probes: Useful for developing activity-based probes and other tools for studying biological pathways.
• Cross-Coupling Reactions: The pinacol boronate ester moiety makes it an ideal partner in palladium-catalyzed Suzuki-Miyaura couplings with aryl halides.

Basic Information

Product Name	1-Cyclohexyl-3-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)phenyl)urea
CAS No.	874299-12-4
Molecular Formula	C19H29BN2O3
Molecular Weight	344.26 g/mol
Synonyms	3-(1-Cyclohexyl-3-ureido)phenylboronic acid pinacol ester; 1-Cyclohexyl-3-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]urea; N-Cyclohexyl-N'-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]urea; Urea, N-cyclohexyl-N'-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-; 874299-12-4; CAS 874299-12-4
EINECS	Contact for details

Quality Control

Our 1-Cyclohexyl-3-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)phenyl)urea is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We can support development and scale-up projects with custom purity grades to meet specific research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when appropriate to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥95% (Standard Grade)
Purity (HPLC)	≥98% (High Purity Grade)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.