Description

1-Cyclopropyl-3-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)phenyl)urea is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its value lies in its dual functionality, combining a protected boronic acid group with a urea linkage, enabling precise cross-coupling reactions and molecular recognition. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and complex organic molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for constructing biaryl scaffolds found in drug candidates.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides requiring specific aryl-boron motifs.
• Material Science Research: Serves as a monomer or functionalization agent in the synthesis of organic electronic materials and polymers.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and inhibitors for studying biological pathways.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses producing specialized fine chemicals for client projects.
• Academic Research: Employed in university and institutional labs for methodological development in organoboron chemistry and catalysis.

Basic Information

Product Name	1-Cyclopropyl-3-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)phenyl)urea
CAS No.	874299-10-2
Molecular Formula	C₁₆H₂₃BN₂O₃
Molecular Weight	302.18 g/mol
Synonyms	3-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-1-cyclopropylurea; N-Cyclopropyl-N'-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]urea; 1-Cyclopropyl-3-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]urea; Urea, N-cyclopropyl-N'-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-; (3-(3-Cyclopropylureido)phenyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Every batch of 1-Cyclopropyl-3-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)phenyl)urea is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high purity and batch-to-batch consistency suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, the container should be kept under an inert atmosphere (e.g., nitrogen or argon) after opening and protected from moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.