Description

1-Isobutyl-3-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Urea is a high-value, functionalized organic compound featuring a urea linkage and a boronic ester pinacol group. This unique structure makes it a critical intermediate or building block in advanced organic synthesis, particularly for the development of pharmaceuticals and agrochemicals. It is primarily sought after by research institutions and industrial R&D departments engaged in medicinal chemistry, where it serves as a key precursor for creating novel bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used extensively in drug discovery for constructing compound libraries via Suzuki-Miyaura cross-coupling reactions.
• Agrochemical Synthesis: Serves as a precursor in the development of new herbicides, fungicides, and plant growth regulators.
• Material Science: Potential use in the synthesis of organic electronic materials and polymers containing boron-nitrogen motifs.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying biological processes and protein interactions.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific synthetic routes.

Basic Information

Product Name	1-Isobutyl-3-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Urea
CAS No.	874299-08-8
Molecular Formula	C17H27BN2O3
Molecular Weight	318.22 g/mol
Synonyms	3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N-(2-methylpropyl)phenylurea; 1-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-3-isobutylurea; N-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-N'-(2-methylpropyl)urea; Urea, N-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-N'-(2-methylpropyl)-; B-[3-[[[(2-Methylpropyl)amino]carbonyl]amino]phenyl]boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 1-Isobutyl-3-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Urea is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This compound is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.