Description

1,1-Diethyl-3-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Urea is a high-purity, advanced pharmaceutical intermediate featuring a protected boronic ester functional group. This compound is critical for modern synthetic chemistry, particularly in the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for applications requiring precise Suzuki-Miyaura cross-coupling reactions.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially kinase inhibitors and other targeted therapies.
• Suzuki-Miyaura Cross-Coupling Reagent: Enables the formation of carbon-carbon bonds in the construction of biaryl structures, a fundamental reaction in medicinal chemistry.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science: Serves as a precursor for organic electronic materials, such as those used in OLEDs and organic semiconductors.
• Chemical Biology Probes: Facilitates the creation of labeled compounds and probes for studying biological pathways and protein interactions.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.

Basic Information

Product Name	1,1-Diethyl-3-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Urea
CAS No.	874298-99-4
Molecular Formula	C19H31BN2O3
Molecular Weight	346.27 g/mol
Synonyms	1,1-Diethyl-3-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]urea; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N,N-diethylphenylurea; 1,1-Diethyl-3-(3-(pinacolboryl)phenyl)urea; Urea, 1,1-diethyl-3-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-; 3-(Pinacolboron)phenyl diethylurea; B-[3-[(Diethylamino)carbonyl]amino]phenyl]boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 1,1-Diethyl-3-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Urea is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.