Description

1-(Furan-2-Ylmethyl)-3-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Urea is a high-value, multifunctional chemical building block that combines a urea linkage with a furan and a boronic ester pinacol group. This compound matters for its critical role in modern synthetic chemistry, particularly in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex molecules. It is primarily needed by research scientists and process chemists in the pharmaceutical and agrochemical industries for drug discovery, development, and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring biaryl linkages.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Material Science Research: Serves as a precursor for creating advanced organic materials, such as polymers and liquid crystals.
• Suzuki-Miyaura Cross-Coupling: The protected boronic ester functionality makes it an ideal, stable reagent for palladium-catalyzed carbon-carbon bond formation.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and library synthesis for lead optimization.
• Chemical Biology: Can be utilized as a probe or linker in bioconjugation chemistry due to its reactive functional groups.

Basic Information

Product Name	1-(Furan-2-Ylmethyl)-3-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Urea
CAS No.	874297-85-5
Molecular Formula	C18H23BN2O4
Molecular Weight	342.20 g/mol
Synonyms	1-[(Furan-2-yl)methyl]-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]urea; N-[(Furan-2-yl)methyl]-N'-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]urea; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl (furan-2-ylmethyl)carbamate (related); Urea, N-[(2-furanylmethyl)]-N'-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-; Boronic acid, B-[4-[[[[(2-furanylmethyl)amino]carbonyl]amino]phenyl]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 1-(Furan-2-Ylmethyl)-3-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Urea is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for research and regulated development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.