Description

4-[(Isopropylcarbamoyl)Amino]Benzeneboronic Acid, Pinacol Ester is a high-purity, protected boronic acid derivative, also known as 4-(3-Isopropylureido)Benzeneboronic Acid, Pinacol Ester, with a CAS number of 874291-02-8. This compound serves as a crucial synthetic intermediate, valued for its stability and reactivity in cross-coupling reactions, which are foundational to modern pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides requiring specific aryl-boronate functionalities.
• Material Science: Precursor for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Biology & Proteomics: Employed in the synthesis of probes and inhibitors for studying enzyme function and protein-protein interactions.
• Catalyst Ligand Synthesis: Serves as a starting material for constructing sophisticated ligand systems used in homogeneous catalysis.
• Academic & Contract Research: Essential reagent for methodological development and synthetic chemistry research in academic and CRO laboratories.

Basic Information

Item	Detail
Product Name	4-[(Isopropylcarbamoyl)Amino]Benzeneboronic Acid, Pinacol Ester / 4-(3-Isopropylureido)Benzeneboronic Acid, Pinacol Ester
CAS No.	874291-02-8
Molecular Formula	C16H25BN2O3
Molecular Weight	304.20 g/mol
Synonyms	4-(3-Isopropylureido)phenylboronic acid pinacol ester; N-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-N'-isopropylurea; 4-(Isopropylcarbamoylamino)benzeneboronic acid pinacol ester; 4-[(Isopropylamino)carbonylamino]benzeneboronic acid pinacol ester; B-[4-[[(1-Methylethyl)amino]carbonyl]amino]phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 874291-02-8; Urea, N-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-N'-isopropyl-
EINECS	Contact for details

Quality Control

Our 4-[(Isopropylcarbamoyl)Amino]Benzeneboronic Acid, Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality system is designed to meet the stringent requirements of pharmaceutical and advanced research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.