Description

1-Propyl-3-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Urea is a high-purity, functionalized boronic ester derivative designed for advanced chemical synthesis. This compound is a critical building block in modern pharmaceutical and agrochemical research, enabling the construction of complex molecules through efficient cross-coupling reactions. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries seeking reliable, high-quality intermediates for their synthetic pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the boronate functional group for structural diversification.
• Material Science: Serves as a monomer or functionalizing agent in the creation of advanced polymers, OLED materials, and organic electronic components.
• Chemical Biology & Proteomics: Employed as a tool compound or linker in the development of chemical probes, inhibitors, and affinity purification reagents.
• Academic & Contract Research: Essential for synthetic methodology development and exploratory chemistry in academic and CRO (Contract Research Organization) laboratories.
• Custom Synthesis: A versatile starting material for the custom synthesis of complex, boron-containing organic molecules for specialized applications.

Basic Information

Product Name	1-Propyl-3-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Urea
CAS No.	874291-01-7
Molecular Formula	C16H25BN2O3
Molecular Weight	304.19 g/mol
Synonyms	1-Propyl-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]urea; N-Propyl-N'-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]urea; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl Propyl Urea; Urea, N-propyl-N'-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-; PINACOL [4-(3-PROPYLUREIDO)PHENYL]BORONATE; [4-(3-Propylureido)phenyl]boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 1-Propyl-3-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Urea is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.