Description

4-[(Ethylcarbamoyl)Amino]Benzeneboronic Acid, Pinacol Ester is a high-purity, organoboron building block crucial for modern synthetic chemistry. This compound, offered at 98% purity, is valued for its stability and reactivity as a protected boronic acid derivative, enabling precise cross-coupling reactions. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers for constructing complex molecular architectures in drug discovery and advanced material synthesis.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of biaryl compounds, a common scaffold in pharmaceuticals and agrochemicals.
• Pharmaceutical Intermediate: Serves as a critical building block in the research and development of new active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Medicinal Chemistry & Drug Discovery: Used in high-throughput screening and library synthesis to explore structure-activity relationships (SAR) and identify novel drug candidates.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as polymers and small molecules for OLEDs or organic photovoltaics.
• Chemical Biology Probes: Acts as a precursor for synthesizing molecules used to study biological processes and protein functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of complex, bespoke organic molecules.

Basic Information

Product Name	4-[(Ethylcarbamoyl)Amino]Benzeneboronic Acid, Pinacol Ester
CAS No.	874291-00-6
Molecular Formula	C16H25BN2O3
Molecular Weight	304.19 g/mol
Synonyms	4-(3-Ethylureido)Benzeneboronic Acid, Pinacol Ester; N-Ethyl-N'-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)urea; 4-(N'-Ethylureido)phenylboronic acid pinacol ester; (4-((Ethylcarbamoyl)amino)phenyl)boronic acid pinacol ester; 2-[4-[(Ethylcarbamoyl)amino]phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; B-[4-[(Ethylamino)carbonyl]amino]phenyl]boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 4-[(Ethylcarbamoyl)Amino]Benzeneboronic Acid, Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the specified 98% standard. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.