Description

4-(Morpholinylcarbonylamino)Phenylboronic Acid, Pinacol Ester is a sophisticated boronic ester derivative, a key building block in modern synthetic chemistry. Its core value lies in its dual functionality, combining a protected boronic acid group for Suzuki-Miyaura cross-coupling reactions with a morpholine carbamate moiety that can serve as a handle for further derivatization. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries engaged in the development of novel small molecule therapeutics and active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs) via palladium-catalyzed cross-coupling reactions.
• Suzuki-Miyaura Cross-Coupling: Serves as a stable, air- and moisture-tolerant boronic ester reagent for constructing biaryl and heterobiaryl scaffolds in drug discovery.
• Medicinal Chemistry Research: Used in high-throughput screening and library synthesis for creating diverse compound sets targeting various disease pathways.
• Agrochemical Synthesis: Employed in the research and development of novel herbicides, fungicides, and insecticides requiring complex aryl-aryl linkages.
• Material Science Precursor: Potential monomer or intermediate in the synthesis of organic electronic materials and advanced polymers.
• Chemical Biology Probes: Can be utilized to create tagged molecules for studying biological processes and protein interactions.

Basic Information

Item	Detail
Product Name	4-(Morpholinylcarbonylamino)Phenylboronic Acid, Pinacol Ester
CAS No.	874290-97-8
Molecular Formula	C18H27BN2O4
Molecular Weight	346.23 g/mol
Synonyms	4-(Morpholine-4-carboxamido)phenylboronic acid pinacol ester; 4-(N-Morpholinocarboxamido)benzeneboronic acid pinacol ester; [4-[(Morpholin-4-yl)formamido]phenyl]boronic acid pinacol ester; PINACOL 4-(MORPHOLIN-4-YLCARBAMOYL)PHENYLBORONATE; B-[4-[(4-Morpholinylcarbonyl)amino]phenyl]-5,5-dimethyl-1,3,2-dioxaborinane; 4-(Morpholinocarbonylamino)benzeneboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our production of 4-(Morpholinylcarbonylamino)Phenylboronic Acid, Pinacol Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support our clients' regulatory needs with traceable documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal stability. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.