Description

4-[(Dimethylcarbamoyl)Amino]Benzeneboronic Acid, Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound matters as a key building block in cross-coupling reactions, enabling the efficient construction of complex molecules for advanced material and pharmaceutical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel compounds and intermediates.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A critical reagent for forming carbon-carbon bonds between aryl halides and this boronic ester, widely used in medicinal chemistry.
• Pharmaceutical Intermediate Synthesis: Serves as a versatile building block for the development of active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides requiring specific aryl-urea or aryl-amide motifs.
• Material Science & OLED Development: Employed in the creation of organic electronic materials, including charge-transport layers and emissive materials for displays.
• Chemical Biology & Probe Development: Useful for synthesizing molecular probes and bioconjugates due to the reactive boronic ester group and protected amine functionality.
• Scale-up Process Chemistry: The pinacol ester protection offers enhanced stability, making it suitable for process development and larger-scale synthesis.

Basic Information

Product Name	4-[(Dimethylcarbamoyl)Amino]Benzeneboronic Acid, Pinacol Ester
CAS No.	874290-93-4
Molecular Formula	C15H23BN2O3
Molecular Weight	290.17 g/mol
Synonyms	4-(3-Dimethylureido)Benzeneboronic Acid, Pinacol Ester; N,N-Dimethyl-N'-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]urea; [4-[(Dimethylcarbamoyl)amino]phenyl]boronic acid pinacol ester; 4-(Dimethylcarbamoylamino)phenylboronic acid pinacol ester; B-[4-[(Dimethylamino)carbonyl]amino]phenyl]boronic acid pinacol ester; 874290-93-4; Pinacol 4-[(Dimethylcarbamoyl)Amino]Benzeneboronate
EINECS	Contact for details

Quality Control

Our 4-[(Dimethylcarbamoyl)Amino]Benzeneboronic Acid, Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.