Description

3-[(4-Chlorophenyl)Carbamoyl]Benzeneboronic Acid is a high-purity, functionalized boronic acid derivative designed for advanced chemical synthesis. This compound serves as a critical building block in cross-coupling reactions, enabling the precise construction of complex molecular architectures. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, leveraging its boronic acid functionality for creating aryl-aryl bonds.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as polymers and small molecules for OLEDs and OFETs.
• Chemical Biology Probes: Acts as a versatile handle for bioconjugation and the development of sensors or inhibitors targeting specific enzymes.
• Catalyst Ligand Preparation: Useful for constructing sophisticated ligand frameworks in transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and libraries for high-throughput screening.

Basic Information

Product Name	3-[(4-Chlorophenyl)Carbamoyl]Benzeneboronic Acid
CAS No.	874288-31-0
Molecular Formula	C13H11BClNO3
Molecular Weight	275.49 g/mol
Synonyms	[3-(4-Chlorophenylcarbamoyl)phenyl]boronic acid; 3-Carbamoylbenzeneboronic acid, 4'-chloro derivative; 3-(4-Chlorophenylaminocarbonyl)benzeneboronic acid; 4-Chloro-N-[3-(dihydroxyboranyl)benzoyl]aniline; B-[3-[[(4-Chlorophenyl)amino]carbonyl]phenyl]boronic acid; 3-(4-Chloroanilinocarbonyl)phenylboronic acid
EINECS	Contact for details

Quality Control

Every batch of 3-[(4-Chlorophenyl)Carbamoyl]Benzeneboronic Acid is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and IR is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.