Description

5-(Dimethylcarbamoyl)-3-Fluorobenzeneboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic organic chemistry. Its value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone of pharmaceutical and advanced materials research. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to construct complex fluorinated and functionalized aromatic scaffolds.

Application

• Pharmaceutical Intermediate: A key reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing fluorinated aromatic systems and amide functionalities.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific fluorinated biphenyl or heterobiaryl structures.
• Material Science Research: Serves as a monomer or building block for creating advanced organic materials, such as polymers, liquid crystals, and organic electronic components.
• Suzuki-Miyaura Cross-Coupling: Primarily employed as an arylboronic acid coupling partner with various aryl/vinyl halides or triflates to form biaryl linkages under palladium catalysis.
• Chemical Biology & Probe Development: Utilized in the design and synthesis of molecular probes and inhibitors for studying biological processes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and small-scale commercial batches.

Basic Information

Item	Detail
Product Name	5-(Dimethylcarbamoyl)-3-Fluorobenzeneboronic Acid
CAS No.	874219-39-3
Molecular Formula	C9H11BFNO3
Molecular Weight	211.00 g/mol
Synonyms	3-Fluoro-5-(dimethylcarbamoyl)benzeneboronic Acid; (3-Fluoro-5-(dimethylcarbamoyl)phenyl)boronic Acid; 5-(Dimethylaminocarbonyl)-3-fluorophenylboronic Acid; 3-Fluoro-N,N-dimethyl-5-boronobenzamide; 874219-39-3; B-(3-Fluoro-5-((dimethylamino)carbonyl)phenyl)boronic acid
EINECS	Contact for details

Quality Control

Our 5-(Dimethylcarbamoyl)-3-Fluorobenzeneboronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF Titration)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.