Description

Fidaxomicin is a narrow-spectrum macrocyclic antibiotic belonging to the lipoglycopeptide class. It is a critical active pharmaceutical ingredient (API) valued for its targeted mechanism of action against specific bacterial pathogens. This compound is primarily required by pharmaceutical manufacturers and research institutions engaged in developing and producing advanced anti-infective therapies.

Application

• Pharmaceutical API: Primary use as the active ingredient in the formulation of oral antibiotic medications.
• Treatment of Clostridioides difficile Infection (CDI): Specifically indicated for the treatment of diarrhea associated with CDI, including initial episodes and recurrences.
• Research & Development: Used in microbiological and pharmacological studies to investigate its spectrum of activity and mechanisms of bacterial inhibition.
• Veterinary Medicine Development: Potential application in developing treatments for bacterial enteric infections in animals.
• Reference Standard: Serves as a high-purity chemical reference standard for analytical testing and quality control in laboratories.

Basic Information

Product Name	Fidaxomicin
CAS No.	873857-62-6
Molecular Formula	C52H74Cl2O18
Molecular Weight	1058.0 g/mol
Synonyms	OPT-80; PAR-101; Difimicin; Tiacumicin B; Lipiarmycin; Clostomicin; Dificid (Brand Name); (3R,4S,5S,6R,8R,9R,10E,12E,15R,16R,17S,18S,19S,20R,21R,24S)-20-[(6-Deoxy-2,3-di-O-methyl-4-O-[(1S)-1-methylpropyl]-β-D-mannopyranosyl)oxy]-6-[[2,6-dideoxy-4-O-(2,6-dideoxy-3-C-methyl-α-L-ribo-hexopyranosyl)-3-C-methyl-α-L-ribo-hexopyranosyl]oxy]-5,17-dihydroxy-3-(1-hydroxyethyl)-16,18,21-trimethyl-8,9,15,24-tetraoxatetracyclo[15.6.1.14,8.019,24]pentacosa-10,12,19,22-tetraene-2,7,14,23-tetrone
EINECS	Contact for details

Quality Control

Our Fidaxomicin is manufactured under strict quality management systems. It undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure compliance with pharmaceutical-grade standards. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each batch to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Microbial Enumeration	Meets Ph. Eur. 2.6.12/2.6.13 criteria

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.