Description

3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Benzene-1,2-Diamine is a high-value, protected boronic ester derivative of o-phenylenediamine, serving as a critical synthetic intermediate. Its primary value lies in enabling Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in pharmaceutical development and advanced material science, where precise molecular assembly is required.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those containing functionalized biphenyl or heterocyclic motifs.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides that require specific biaryl architectures for efficacy.
• Organic Light-Emitting Diodes (OLEDs): Serves as a precursor for electron-transport materials and emissive layer components in display and lighting technologies.
• Ligand Synthesis for Catalysis: Enables the construction of sophisticated bidentate nitrogen ligands used in asymmetric catalysis and transition metal complexes.
• Polymer Chemistry: Incorporated into monomers for producing specialty polymers with tailored thermal, mechanical, or electronic properties.
• Chemical Biology & Proteomics: Utilized in probe and linker synthesis for studying protein interactions and enzyme activity.
• Academic & Contract Research: A valuable reagent for methodological development and exploratory synthesis in academic and industrial R&D laboratories.

Basic Information

Product Name	3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Benzene-1,2-Diamine
CAS No.	873663-50-4
Molecular Formula	C12H19BN2O2
Molecular Weight	234.11 g/mol
Synonyms	1,2-Diamino-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzene; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzene-1,2-diamine; 2-Amino-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline; o-Phenylenediamine-3-boronic acid pinacol ester; 3-Borono-1,2-phenylenediamine pinacol ester; 3-(Pinacolatoboryl)-1,2-benzenediamine
EINECS	Contact for details

Quality Control

Our 3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Benzene-1,2-Diamine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical characterization, including HPLC for purity assessment and NMR for structural confirmation, to ensure consistency and reliability for sensitive synthetic applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent decomposition.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.