Description

Ethyl 5-Fluoro-2-Methoxybenzoylformate is a high-purity fluorinated aromatic ester building block, essential for advanced organic synthesis. Its core value lies in providing a reactive α-ketoester moiety adjacent to a fluorine-substituted methoxybenzene ring, enabling precise molecular construction. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of fluorinated drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Chemical Research: Serves as a versatile precursor for heterocyclic chemistry, enabling the construction of complex fluorinated scaffolds like quinazolines and benzoxazines.
• Material Science: Potential monomer or additive in the development of specialty polymers and advanced organic electronic materials.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific projects requiring fluorinated aromatic compounds.

Basic Information

Product Name	Ethyl 5-Fluoro-2-Methoxybenzoylformate
CAS No.	873548-10-8
Molecular Formula	C11H11FO4
Molecular Weight	226.20 g/mol
Synonyms	Ethyl 5-Fluoro-2-methoxy-α-oxobenzeneacetate; Ethyl (5-Fluoro-2-methoxyphenyl)(oxo)acetate; 2-Methoxy-5-fluorobenzoylformic Acid Ethyl Ester; 5-Fluoro-2-methoxybenzoylformic Acid Ethyl Ester; α-Oxo-5-fluoro-2-methoxybenzeneacetic Acid Ethyl Ester; Ethyl α-Oxo-5-fluoro-2-methoxybenzeneacetate; Ethyl 2-Methoxy-5-fluorobenzoylformate
EINECS	Contact for details

Quality Control

Our Ethyl 5-Fluoro-2-Methoxybenzoylformate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment ensures the material meets the stringent requirements for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.