Description

E-2-Chloromethylvinylboronic Acid Pinacol Ester is a high-value organoboron building block, specifically a protected vinylboronic ester derivative. This compound is essential for enabling advanced cross-coupling reactions, such as Suzuki-Miyaura couplings, to construct complex molecular architectures with precision. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for synthesizing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key reagent in the synthesis of novel drug candidates, particularly for creating complex alkenyl and substituted vinyl segments.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides requiring specific vinyl functionalization.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialized polymers and organic electronic materials.
• Suzuki-Miyaura Cross-Coupling: The primary application is as a versatile coupling partner with various aryl or vinyl halides to form new carbon-carbon bonds.
• Chemical Research & Development: Employed in academic and industrial labs for methodology development and the construction of complex organic molecules.
• Ligand and Catalyst Preparation: Useful for synthesizing novel boron-containing ligands for metal catalysis.

Basic Information

Product Name	E-2-Chloromethylvinylboronic Acid Pinacol Ester
CAS No.	873077-21-5
Molecular Formula	C9H16BClO2
Molecular Weight	202.49 g/mol
Synonyms	(E)-2-(Chloromethyl)ethenylboronic Acid Pinacol Ester; (E)-2-(Chloromethyl)vinylboronic Acid Pinacol Ester; B-[(1E)-2-Chloroethenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4,4,5,5-Tetramethyl-2-[(E)-2-chlorovinyl]-1,3,2-dioxaborolane; (E)-2-Chlorovinylboronic Acid Pinacol Ester; trans-2-Chloromethylvinylboronic Acid Pinacol Ester; Pinacol (E)-2-(Chloromethyl)vinylboronate
EINECS	Contact for details

Quality Control

Our E-2-Chloromethylvinylboronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and production. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality system is designed to meet the stringent requirements of pharmaceutical and advanced chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Isomeric Purity (E/Z Ratio)	≥ 95:5 (E:Z)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.