Description

4-Formyl-3-Iodobenzotrifluoride, 2-Iodo-Alpha,Alpha,α-Trifluoro-p-Tolualdehyde is a high-value, multi-functional aromatic building block characterized by its unique combination of an aldehyde group, an iodine substituent, and a trifluoromethyl group on the benzene ring. This trifunctional structure makes it a critical intermediate for synthesizing complex molecules where precise electronic and steric properties are required. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of fluorine-containing drugs where the trifluoromethyl group enhances metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides, leveraging the iodine atom for further cross-coupling reactions to attach complex side chains.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis, especially in C-C and C-N cross-coupling reactions.
• Advanced Material Precursor: Employed in the research and production of organic electronic materials, such as OLEDs and semiconductors, where the fluorine and aldehyde functionalities tune electronic properties.
• Custom Chemical Synthesis: A versatile starting material for contract research organizations (CROs) and custom synthesis units to produce tailored compounds for client-specific projects.
• Fluorine Chemistry Research: Essential reagent in academic and industrial labs studying the introduction and reactivity of fluorine atoms in aromatic systems.

Basic Information

Item	Details
Product Name	4-Formyl-3-Iodobenzotrifluoride, 2-Iodo-Alpha,Alpha,α-Trifluoro-p-Tolualdehyde
CAS No.	873006-01-0
Molecular Formula	C8H4F3IO
Molecular Weight	300.02 g/mol
Synonyms	2-Iodo-α,α,α-trifluoro-p-tolualdehyde; 3-Iodo-4-formylbenzotrifluoride; 4-Formyl-3-iodobenzotrifluoride; 2-Iodo-4-(trifluoromethyl)benzaldehyde; 3-Iodo-α,α,α-trifluoro-p-tolualdehyde; 4-(Trifluoromethyl)-2-iodobenzaldehyde; 2-Iodo-α,α,α-trifluoro-4-methylbenzaldehyde
EINECS	Contact for details

Quality Control

Every batch of 4-Formyl-3-Iodobenzotrifluoride is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards, and our specifications are designed to meet the rigorous demands of research and scale-up synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residue on Ignition	< 0.1%
Solubility	Soluble in common organic solvents

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.