Description

6-(Trifluoromethyl)Benzofuran-3(2H)-One is a high-value, fluorinated heterocyclic building block essential for advanced organic synthesis. This compound is prized for its ability to impart unique physicochemical properties, such as enhanced metabolic stability and lipophilicity, to target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the design and synthesis of advanced pesticides and herbicides, where the trifluoromethyl group can improve biological activity and environmental persistence.
• Material Science Precursor: Serves as a building block for specialty polymers, liquid crystals, and organic electronic materials due to its aromatic and electron-withdrawing characteristics.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development, library synthesis, and exploring new chemical spaces in fluoroorganic chemistry.
• Fluorine Chemistry Reagent: Acts as a versatile substrate for further functionalization via cross-coupling, reduction, or nucleophilic substitution reactions to create diverse chemical libraries.

Basic Information

Product Name	6-(Trifluoromethyl)Benzofuran-3(2H)-One
CAS No.	872191-30-5
Molecular Formula	C9H5F3O2
Molecular Weight	202.13 g/mol
Synonyms	6-(Trifluoromethyl)-3(2H)-benzofuranone; 6-(Trifluoromethyl)-2,3-dihydro-1-benzofuran-3-one; 3-Hydroxy-6-(trifluoromethyl)benzofuran; 6-Trifluoromethyl-3-coumaranone; 2,3-Dihydro-6-(trifluoromethyl)benzofuran-3-one; 872191-30-5; 6-Trifluoromethylbenzofuran-3-one
EINECS	Contact for details

Quality Control

Our 6-(Trifluoromethyl)Benzofuran-3(2H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.