Description

5-Methylpyridine-2-Boronic Acid n-Phenyldiethanolamine Ester is a specialized boronic ester derivative, a crucial building block in modern synthetic chemistry. Its primary value lies in its role as a protected boronic acid moiety, offering enhanced stability and solubility for use in cross-coupling reactions, most notably the Suzuki-Miyaura reaction. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients and complex organic molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing biaryl or heterobiaryl structures.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require specific pyridine-based scaffolds.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of organic electronic materials, such as OLEDs and conductive polymers.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for transition metal catalysts used in asymmetric synthesis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: A critical reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	5-Methylpyridine-2-Boronic Acid n-Phenyldiethanolamine Ester
CAS No.	872054-54-1
Molecular Formula	C16H21BN2O2
Molecular Weight	284.16 g/mol
Synonyms	2-(5-Methylpyridin-2-yl)-1,3,2-dioxaborinane, 4,4-Diphenyl Derivative; 5-Methyl-2-pyridineboronic Acid N-Phenyldiethanolamine Ester; B-(5-Methyl-2-pyridinyl)-N-phenyldiethanolamine Boronate; Boronic Acid, B-(5-Methyl-2-pyridinyl)-, N-Phenyldiethanolamine Ester; 872054-54-1; 5-Methylpyridine-2-boronic Acid PhDEA Ester
EINECS	Contact for details

Quality Control

Every batch of 5-Methylpyridine-2-Boronic Acid n-Phenyldiethanolamine Ester is produced and tested under strict quality management systems. We ensure compliance with relevant industry standards for fine chemical intermediates. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing purity, identity, and impurity profiles as confirmed by advanced analytical techniques including NMR and HPLC.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.