Description

Benzonitrile, 4-[7-Hydroxy-8-Methoxy-2-(1-Methylethyl)-4-Oxo-3(4H)-Quinazolinyl]- is a specialized quinazolinone derivative, a high-value synthetic intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a key building block in the development of novel pharmaceutical agents and bioactive molecules, particularly those targeting specific enzymatic pathways. Industrial and academic researchers in the pharmaceutical, agrochemical, and fine chemical sectors need this precise chemical for constructing complex molecular architectures in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, especially those with quinazolinone-based pharmacophores.
• Medicinal Chemistry Research: Used as a scaffold or building block for constructing libraries of novel compounds in high-throughput screening and structure-activity relationship (SAR) studies.
• Agrochemical Development: Employed in the research and synthesis of new-generation herbicides, fungicides, or plant growth regulators.
• Biochemical Tool Compound: May be utilized in biochemical assays to study enzyme inhibition or modulate specific biological pathways in research settings.
• Fine Chemical Synthesis: Acts as a specialized reagent for introducing the benzonitrile-quinazolinone moiety into more complex organic molecules.
• Academic & Contract Research: Essential for universities and CROs (Contract Research Organizations) engaged in cutting-edge organic synthesis and heterocyclic chemistry projects.

Basic Information

Product Name	Benzonitrile, 4-[7-Hydroxy-8-Methoxy-2-(1-Methylethyl)-4-Oxo-3(4H)-Quinazolinyl]-
CAS No.	871814-49-2
Molecular Formula	C19H17N3O4
Molecular Weight	351.36 g/mol
Synonyms	4-(7-Hydroxy-8-methoxy-2-isopropyl-4-oxo-3,4-dihydroquinazolin-3-yl)benzonitrile; 2-Isopropyl-7-hydroxy-8-methoxy-3-(4-cyanophenyl)-4(3H)-quinazolinone; 3-(4-Cyanophenyl)-2-isopropyl-7-hydroxy-8-methoxy-4(3H)-quinazolinone; 4-(7-Hydroxy-8-methoxy-2-propan-2-yl-4-oxo-3H-quinazolin-3-yl)benzonitrile; Benzonitrile derivative (CAS 871814-49-2); Quinazolinone benzonitrile derivative; 3-(4-Cyanophenyl)-7-hydroxy-8-methoxy-2-(1-methylethyl)-4(3H)-quinazolinone
EINECS	Contact for details

Quality Control

Our Benzonitrile, 4-[7-Hydroxy-8-Methoxy-2-(1-Methylethyl)-4-Oxo-3(4H)-Quinazolinyl]- is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality systems are designed to meet the stringent requirements of pharmaceutical R&D and fine chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.