Description

2-(Fluoromethyl)-1-Methyl-1H-Imidazole is a specialized fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key precursor in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where the introduction of a fluorine atom can dramatically alter biological activity and metabolic stability. Pharmaceutical researchers, agrochemical developers, and fine chemical manufacturers need this high-purity intermediate to create next-generation compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and development of new generation pesticides, herbicides, and fungicides, where fluorination improves efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized N-heterocyclic carbene (NHC) ligands and other organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of fluorinated ionic liquids, polymers, and advanced materials with unique electrochemical or surface properties.
• Chemical Biology Probes: Utilized to create fluorinated analogs of biomolecules for studying enzyme mechanisms and protein-ligand interactions.

Basic Information

Product Name	2-(Fluoromethyl)-1-Methyl-1H-Imidazole
CAS No.	871507-59-4
Molecular Formula	C5H7FN2
Molecular Weight	114.12 g/mol
Synonyms	1-Methyl-2-(fluoromethyl)-1H-imidazole; 2-(Fluoromethyl)-1-methylimidazole; 1-Methyl-2-fluoromethylimidazole; 2-Fluoromethyl-1-methylimidazole; Fluoromethyl methylimidazole; FMI; 871507-59-4; SCHEMBL2184221
EINECS	Contact for details

Quality Control

Our 2-(Fluoromethyl)-1-Methyl-1H-Imidazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification parameters. Our quality commitment supports applications in GMP and ISO-regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.