Description

cis-3-Hydroxy-2-Phenyl-3A,4,5,6,7,7A-Hexahydroinden-1-One CAS NO 871482-77-8 is a high-purity, advanced pharmaceutical intermediate characterized by its specific stereochemistry and functional groups. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) and fine chemicals, where precise molecular structure dictates biological activity and process efficiency. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new therapeutic agents and high-value chemical entities.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its complex bicyclic structure.
• Asymmetric Catalysis Research: Serves as a precursor or ligand in the development of new catalytic systems for stereoselective synthesis.
• Fine Chemical Production: Employed in the manufacture of specialty fragrances, flavors, and other high-value performance chemicals.
• Academic & R&D: A valuable compound for methodological studies in organic synthesis, medicinal chemistry, and process chemistry within university and corporate laboratories.

Basic Information

Item	Details
Product Name	cis-3-Hydroxy-2-Phenyl-3A,4,5,6,7,7A-Hexahydroinden-1-One
CAS No.	871482-77-8
Molecular Formula	C15H16O2
Molecular Weight	228.29 g/mol
Synonyms	cis-3-Hydroxy-2-phenyl-3a,4,5,6,7,7a-hexahydro-1H-inden-1-one; 2-Phenyl-cis-hexahydroinden-1-one-3-ol; (3S,3aR,7aR)-3-Hydroxy-2-phenyl-3a,4,5,6,7,7a-hexahydro-1H-inden-1-one; (3R,3aS,7aS)-3-Hydroxy-2-phenyl-3a,4,5,6,7,7a-hexahydro-1H-inden-1-one; Hexahydroindenone derivative; Chiral indanone intermediate
EINECS	Contact for details

Quality Control

Our cis-3-Hydroxy-2-Phenyl-3A,4,5,6,7,7A-Hexahydroinden-1-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure compliance with exacting standards for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.