Description

cis-3-Hydroxy-2-Methyl-3A,4,5,6,7,7A-Hexahydroinden-1-One CAS NO 871482-67-6 is a high-purity, advanced pharmaceutical intermediate characterized by its specific stereochemistry and functionalized hexahydroindenone core structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) where precise molecular architecture dictates biological activity. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and fine chemical sectors for developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of proprietary drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• Asymmetric Synthesis: Utilized in stereoselective chemical reactions to construct complex molecules with high enantiomeric purity.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring specific stereocenters.
• Reference Standard: Used as an analytical standard for quality control and method development in pharmaceutical laboratories.

Basic Information

Product Name	cis-3-Hydroxy-2-Methyl-3A,4,5,6,7,7A-Hexahydroinden-1-One
CAS No.	871482-67-6
Molecular Formula	C10H14O2
Molecular Weight	166.22 g/mol
Synonyms	cis-3-Hydroxy-2-methyl-3a,4,5,6,7,7a-hexahydro-1H-inden-1-one; 2-Methyl-3-hydroxy-3a,4,5,6,7,7a-hexahydroinden-1-one; (3S,3aR,7aR)-3-Hydroxy-2-methyl-3a,4,5,6,7,7a-hexahydro-1H-inden-1-one; (3R,3aS,7aS)-3-Hydroxy-2-methyl-3a,4,5,6,7,7a-hexahydro-1H-inden-1-one; Hexahydroindenone derivative; Chiral hydroxy ketone intermediate.
EINECS	Contact for details

Quality Control

Our cis-3-Hydroxy-2-Methyl-3A,4,5,6,7,7A-Hexahydroinden-1-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.