Description

n-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzylidene)-4-Methoxybenzenamine is a high-value, specialized boronic ester derivative used as a key synthetic intermediate. This compound matters for its role as a versatile building block in modern organic synthesis, particularly in cross-coupling reactions. Pharmaceutical researchers, agrochemical developers, and advanced materials scientists need it for constructing complex molecular architectures, including potential active pharmaceutical ingredients (APIs) and functional organic materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging the boronate functional group for selective bond formation.
• Organic Electronics: Serves as a monomer or building block for creating conjugated polymers and small molecules used in OLEDs, OFETs, and other organic semiconductor applications.
• Material Science Research: Employed in the synthesis of metal-organic frameworks (MOFs), covalent organic frameworks (COFs), and other porous materials for catalysis and gas storage.
• Chemical Biology & Proteomics: Acts as a handle for bioconjugation or as part of molecular probes for studying biological processes and protein interactions.
• Academic & R&D Laboratories: A valuable reagent for methodological development in synthetic organic chemistry and catalysis research.

Basic Information

Product Name	n-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzylidene)-4-Methoxybenzenamine
CAS No.	871366-38-0
Molecular Formula	C20H24BNO3
Molecular Weight	337.22 g/mol
Synonyms	4-Methoxy-N-[[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methylene]benzenamine; (E)-N-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzylidene)-4-methoxyaniline; 4-Methoxy-N-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methylene)aniline; 4-Methoxy-N-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzylidene)aniline; Benzenamine, N-[[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methylene]-4-methoxy-; Pinacol (E)-[4-[(4-Methoxyphenyl)iminomethyl]phenyl]boronate
EINECS	Contact for details

Quality Control

Our n-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzylidene)-4-Methoxybenzenamine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data including HPLC purity, NMR (1H, 13C, and 11B), and mass spectrometry for identity confirmation. A detailed Certificate of Analysis (COA) is supplied with each batch, and we support custom synthesis to meet specific R&D or scale-up requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent potential degradation and moisture absorption. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.