Description

4-Chloro-3-(Cyclohexylaminocarbonyl)Phenylboronic Acid is a sophisticated boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its dual functionality, combining a reactive boronic acid group with a chlorinated aromatic ring and a cyclohexylamide moiety, making it an essential intermediate for constructing complex molecular architectures. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in Suzuki-Miyaura cross-coupling reactions and medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific aryl-chloro and boronic acid functionalities.
• Material Science Research: Serves as a monomer or precursor for creating advanced organic materials, such as polymers and liquid crystals.
• Chemical Biology & Probe Development: Utilized in the design and synthesis of molecular probes and biochemical tools for target identification and validation.
• Catalyst Ligand Precursor: Acts as a starting material for synthesizing specialized ligands used in homogeneous catalysis.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	4-Chloro-3-(Cyclohexylaminocarbonyl)Phenylboronic Acid
CAS No.	871332-92-2
Molecular Formula	C13H17BClNO3
Molecular Weight	281.54 g/mol
Synonyms	[4-Chloro-3-(cyclohexylaminocarbonyl)phenyl]boronic acid; (4-Chloro-3-((cyclohexylamino)carbonyl)phenyl)boronic acid; Boronic acid, B-[4-chloro-3-[[(cyclohexylamino)carbonyl]]phenyl]-; 4-Chloro-3-(cyclohexylcarbamoyl)phenylboronic acid; 3-Carbamoyl-4-chlorophenylboronic acid, N-cyclohexyl-; 871332-92-2; B-(4-Chloro-3-cyclohexylaminocarbonylphenyl)boronic acid
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-(Cyclohexylaminocarbonyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing batch-specific results are available upon request, supporting compliance with research and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.