Description

3-(T-Butylcarbamoyl)-5-Nitrophenylboronic Acid is a specialized organoboron compound that serves as a critical building block in modern synthetic chemistry. Its molecular architecture, featuring both a boronic acid group and a nitro-substituted aromatic ring, makes it a valuable reagent for constructing complex molecules via cross-coupling reactions. This high-purity intermediate is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its boronic acid functionality for creating diverse bioactive compounds.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of organic electronic materials and advanced polymers.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme activity and protein interactions.
• Catalyst Ligand Development: Acts as a starting material for synthesizing sophisticated ligands used in homogeneous catalysis.
• Custom Synthesis & Contract Manufacturing: A vital component for CDMOs (Contract Development and Manufacturing Organizations) offering bespoke chemical synthesis services.

Basic Information

Product Name	3-(T-Butylcarbamoyl)-5-Nitrophenylboronic Acid
CAS No.	871332-87-5
Molecular Formula	C11H15BN2O5
Molecular Weight	266.06 g/mol
Synonyms	3-[(tert-Butylcarbamoyl)]-5-nitrophenylboronic Acid; 5-Nitro-3-[(tert-butylamino)carbonyl]benzeneboronic Acid; 3-(tert-Butylcarbamoyl)-5-nitrobenzeneboronic Acid; B-[3-[(1,1-Dimethylethyl)amino]carbonyl]-5-nitrophenyl]boronic Acid; 3-(Tert-butylaminocarbonyl)-5-nitrophenylboronic Acid; 871332-87-5; Boronic acid, B-[3-[[(1,1-dimethylethyl)amino]carbonyl]-5-nitrophenyl]-
EINECS	Contact for details

Quality Control

Every batch of 3-(T-Butylcarbamoyl)-5-Nitrophenylboronic Acid is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our standard pharmaceutical intermediate grade meets stringent internal specifications, with purity typically exceeding 97% (HPLC). A detailed Certificate of Analysis (COA) documenting assay, related substances, and physical characteristics is provided with each shipment. We support compliance with cGMP and REACH requirements for our global clientele.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability. Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.