Description

4-Chloro-3-(Isopropylcarbamoyl)Phenylboronic Acid is a high-purity boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its dual functionality, combining a reactive boronic acid group with a chloro-substituted aromatic carboxamide, making it an essential intermediate for cross-coupling reactions. This compound is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of complex biaryl structures for pharmaceutical candidates.
• Pharmaceutical Intermediate: Used in the research and development of novel drug molecules, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Serves as a precursor in creating advanced herbicides and fungicides with targeted activity.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as polymers for OLEDs or organic photovoltaics.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis houses serving the life sciences industry.

Basic Information

Product Name	4-Chloro-3-(Isopropylcarbamoyl)Phenylboronic Acid
CAS No.	871332-74-0
Molecular Formula	C10H13BClNO3
Molecular Weight	241.48 g/mol
Synonyms	[4-Chloro-3-(isopropylcarbamoyl)phenyl]boronic acid; (4-Chloro-3-((isopropylamino)carbonyl)phenyl)boronic acid; Boronic acid, B-[4-chloro-3-[[(1-methylethyl)amino]carbonyl]phenyl]-; 4-Chloro-3-(isopropylaminocarbonyl)benzeneboronic acid; 3-Carbamoyl-4-chlorophenylboronic acid isopropyl derivative; CAS 871332-74-0
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-(Isopropylcarbamoyl)Phenylboronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or when opening the container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.