Description

4-Chloro-3-(Ethylcarbamoyl)Phenylboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic chemistry. Its value lies in enabling precise Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, especially those containing biphenyl or heterocyclic scaffolds.
• Agrochemical Research: Used to create advanced active ingredients for crop protection products through palladium-catalyzed coupling.
• Material Science: Serves as a precursor for functionalized polymers, organic electronic materials, and metal-organic frameworks (MOFs).
• Chemical Synthesis: Enables the efficient formation of carbon-carbon bonds in complex multi-step synthetic routes for fine chemicals.
• Ligand & Catalyst Development: Utilized in the preparation of specialized boronic acid-based ligands for catalysis and sensing applications.

Basic Information

Product Name	4-Chloro-3-(Ethylcarbamoyl)Phenylboronic Acid
CAS No.	871332-69-3
Molecular Formula	C9H11BClNO3
Molecular Weight	227.45 g/mol
Synonyms	4-Chloro-3-(ethylaminocarbonyl)benzeneboronic acid; [4-Chloro-3-(ethylcarbamoyl)phenyl]boronic acid; 2-Chloro-5-boronobenzamide, N-ethyl-; B-[4-Chloro-3-[(ethylamino)carbonyl]phenyl]boronic acid; 4-Chloro-N-ethyl-3-boronobenzamide; 871332-69-3; (4-Chloro-3-(ethylcarbamoyl)phenyl)boronic acid
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-(Ethylcarbamoyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.