Description

5-(n-Benzylsulfamoyl)-2-Methylphenylboronic Acid is a specialized organoboron compound featuring a unique sulfamoyl-benzyl substituent, making it a valuable building block in modern synthetic chemistry. Its core value lies in its dual functionality, serving as both a protected amine precursor and a boronic acid for cross-coupling reactions, which is critical for constructing complex molecular architectures. This high-purity intermediate is essential for researchers and process chemists in the pharmaceutical and agrochemical industries engaged in developing new active ingredients, particularly through Suzuki-Miyaura coupling methodologies.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, especially for targeted therapies.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a critical boronic acid partner for forming carbon-carbon bonds in complex molecule synthesis.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides requiring specific aryl-aryl linkages.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology Probes: Utilized for synthesizing labeled compounds and probes for biochemical and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses producing bespoke compounds for client projects.

Basic Information

Product Name	5-(n-Benzylsulfamoyl)-2-Methylphenylboronic Acid
CAS No.	871329-73-6
Molecular Formula	C14H16BNO4S
Molecular Weight	305.16 g/mol
Synonyms	2-Methyl-5-[(phenylmethyl)sulfamoyl]benzeneboronic Acid; [2-Methyl-5-(N-benzylsulfamoyl)phenyl]boronic Acid; 5-(Benzylsulfamoyl)-2-methylbenzeneboronic Acid; B-[2-Methyl-5-[(phenylmethyl)sulfamoyl]phenyl]boronic Acid; 2-Methyl-5-(N-benzylsulfamoyl)phenylboronic Acid; 871329-73-6; 5-(N-Benzylsulfamoyl)-o-tolylboronic Acid
EINECS	Contact for details

Quality Control

Every batch of 5-(n-Benzylsulfamoyl)-2-Methylphenylboronic Acid is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure consistency and high purity. Our standard grade meets specifications suitable for research and process development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.