Description

3-Amino-5-Nitrobenzeneboronic Acid Pinacol Ester is a high-value, multifunctional boronic ester derivative, serving as a critical synthetic intermediate in modern organic and medicinal chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to develop active pharmaceutical ingredients (APIs), novel crop protection agents, and functional organic materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides with targeted activity.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile arylboron reagent for palladium-catalyzed C-C bond formation to create biaryl and heterobiaryl structures.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs).
• Chemical Biology & Proteomics: Utilized as a handle for bioconjugation and the development of chemical probes and sensors.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring functionalized aromatic boronic esters.

Basic Information

Item	Detail
Product Name	3-Amino-5-Nitrobenzeneboronic Acid Pinacol Ester
CAS No.	871329-51-0
Molecular Formula	C12H17BN2O4
Molecular Weight	264.09 g/mol
Synonyms	5-Nitro-3-aminobenzeneboronic Acid Pinacol Ester; (3-Amino-5-nitrophenyl)boronic Acid Pinacol Ester; 3-Amino-5-nitrophenylboronic Acid Pinacol Ester; 3-Amino-5-nitrobenzeneboronic Acid, Pinacol Ester; 3-Amino-5-nitrobenzeneboronic Acid Pinacol Cyclic Ester; 2-(3-Amino-5-nitrophenyl)-5,5-dimethyl-1,3,2-dioxaborinane; Pinacol (3-Amino-5-nitrophenyl)boronate
EINECS	Contact for details

Quality Control

Our 3-Amino-5-Nitrobenzeneboronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ISO standards for research and commercial-scale applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.