Description

4-(3'-Bromobenzyloxy)Phenylboronic Acid is a high-purity boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its value lies in its dual functionality, serving as a key intermediate in cross-coupling reactions like the Suzuki-Miyaura reaction, which is fundamental for constructing complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery, ligand synthesis, and the development of functional organic molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biaryl or complex aromatic scaffolds.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile boronic acid coupling partner for forming carbon-carbon bonds with aryl halides, a cornerstone reaction in medicinal and process chemistry.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific aromatic architectures.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for transition metal catalysts or as a component in metal-organic frameworks (MOFs).
• Material Science Research: Acts as a monomer or building block for synthesizing organic electronic materials, polymers, and liquid crystals.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target identification.

Basic Information

Product Name	4-(3'-Bromobenzyloxy)Phenylboronic Acid
CAS No.	871126-12-4
Molecular Formula	C13H12BBrO3
Molecular Weight	307.95 g/mol
Synonyms	[4-(3-Bromobenzyloxy)phenyl]boronic acid; 4-(3-Bromobenzyloxy)benzeneboronic acid; (4-((3-Bromobenzyl)oxy)phenyl)boronic acid; B-[4-[(3-Bromophenyl)methoxy]phenyl]boronic acid; 3-Bromo-4'-benzyloxybenzeneboronic acid; Boronic acid, B-[4-[(3-bromophenyl)methoxy]phenyl]-; 4-(3-Bromobenzyloxy)phenylboronic acid pinacol ester (common protected form).
EINECS	Contact for details

Quality Control

Our 4-(3'-Bromobenzyloxy)Phenylboronic Acid is manufactured under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, assay, and impurity profiles to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or when opening the container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.