Description

1-(2,6-Difluorophenyl)Ethan-1-Amine is a high-purity fluorinated aromatic amine building block of significant importance in advanced organic synthesis. This compound serves as a critical intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its difluorophenyl moiety can impart desirable metabolic stability and bioavailability. It is primarily needed by research and development chemists, process development teams, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require fluorinated aromatic structures.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the creation of novel fluorinated polymers and advanced organic electronic materials.
• Chemical Biology Probes: Utilized as a building block for fluorescent tags and molecular probes in diagnostic research.
• Custom Synthesis and Contract Manufacturing: Supplied to CROs and CDMOs for client-specific research and scale-up projects.

Basic Information

Product Name	1-(2,6-Difluorophenyl)Ethan-1-Amine
CAS No.	870849-40-4
Molecular Formula	C8H9F2N
Molecular Weight	157.16 g/mol
Synonyms	α-Methyl-2,6-difluorobenzylamine; 1-(2,6-Difluorophenyl)ethanamine; 2,6-Difluoro-α-methylbenzylamine; (2,6-Difluorophenyl)ethanamine; 1-Aminoethyl-2,6-difluorobenzene; 870849-40-4; 1-(2,6-Difluorophenyl)ethylamine
EINECS	Contact for details

Quality Control

Our 1-(2,6-Difluorophenyl)Ethan-1-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This amine compound should be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent oxidation and moisture absorption. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.