Description

1-(3-Formylphenyl)Piperazine is a versatile aromatic aldehyde derivative of piperazine, serving as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both a formyl group and a piperazine ring, makes it an essential intermediate for constructing complex molecular architectures. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various drug candidates, particularly those targeting central nervous system (CNS) disorders, due to the piperazine pharmacophore.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides where the phenylpiperazine scaffold imparts specific biological activity.
• Ligand and Catalyst Development: Employed in the preparation of chelating ligands for metal catalysts used in asymmetric synthesis and cross-coupling reactions.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the production of specialty polymers with tailored thermal or mechanical properties.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Dye and Pigment Intermediate: Utilized in the synthesis of complex organic dyes and pigments, leveraging its aromatic aldehyde functionality.

Basic Information

Item	Details
Product Name	1-(3-Formylphenyl)Piperazine
CAS No.	870703-56-3
Molecular Formula	C11H14N2O
Molecular Weight	190.24 g/mol
Synonyms	3-(Piperazin-1-yl)benzaldehyde; 1-(3-Formylphenyl)piperazine; 3-Piperazin-1-ylbenzaldehyde; m-Formylphenylpiperazine; 3-(1-Piperazinyl)benzaldehyde; 1-(3-Carboxaldehydephenyl)piperazine; Benzaldehyde, 3-(1-piperazinyl)-
EINECS	Contact for details

Quality Control

Our 1-(3-Formylphenyl)Piperazine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request. We adhere to cGMP standards where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.