Description

(4'-Cyano-[1,1'-Biphenyl]-3-Yl)Boronic Acid Pinacol Ester is a high-purity, synthetically valuable boronic ester derivative. This compound serves as a crucial advanced pharmaceutical intermediate and building block in modern organic synthesis, particularly in cross-coupling reactions. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex biphenyl-based molecular architectures.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for the palladium-catalyzed formation of carbon-carbon bonds, enabling the synthesis of complex biaryl structures prevalent in active pharmaceutical ingredients (APIs).
• Pharmaceutical Intermediate: Serves as a critical building block in the research and development of novel drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and inflammatory diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides that require specific biphenyl scaffolds for enhanced efficacy and selectivity.
• Liquid Crystal and OLED Material Research: Acts as a precursor for creating organic electronic materials, including charge-transport layers and emissive compounds for display technologies.
• Metal-Organic Framework (MOF) Construction: Employed as an organic linker in the synthesis of porous coordination polymers for gas storage, separation, and catalysis.
• Chemical Biology and Probe Development: Utilized in the synthesis of molecular probes and labeled compounds for biochemical assays and diagnostic applications.

Basic Information

Product Name	(4'-Cyano-[1,1'-Biphenyl]-3-Yl)Boronic Acid Pinacol Ester
CAS No.	870244-08-9
Molecular Formula	C20H22BNO2
Molecular Weight	319.21 g/mol
Synonyms	3-(4'-Cyanobiphenyl-4-yl)boronic acid pinacol ester; [1,1'-Biphenyl]-3-boronic acid, 4'-cyano-, 1,1-dimethylethyl ester; 4'-Cyano-[1,1'-biphenyl]-3-ylboronic acid pinacol ester; 3-(4-Cyanophenyl)phenylboronic acid pinacol ester; PINACOL (4'-CYANO-[1,1'-BIPHENYL]-3-YL)BORONATE; (3-(4'-Cyanobiphenyl-4-yl)phenyl)boronic acid pinacol ester; B-[3-(4-Cyanophenyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our (4'-Cyano-[1,1'-Biphenyl]-3-Yl)Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high chemical purity and structural integrity suitable for sensitive cross-coupling applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee batch-to-batch consistency and support your regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening the container for use to prevent hydrolysis and maintain reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.