Description

4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenylethynyl-Trimethylsilane is a high-value organoboron building block featuring both a protected boronic ester and a silyl-protected alkyne functional group. This compound is critical for advanced cross-coupling reactions, particularly in the synthesis of complex organic molecules and functional materials. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for constructing carbon-carbon bonds with precision.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides requiring specific aryl-alkyne architectures.
• Organic Electronic Materials: Serves as a building block for conjugated polymers and small molecules used in OLEDs, OFETs, and solar cells.
• Ligand and Catalyst Development: Employed in the preparation of sophisticated ligands and organometallic catalysts for asymmetric synthesis.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for bio-conjugation and imaging applications.
• Polymer Chemistry: Acts as a monomer or chain extender in the synthesis of specialty polymers with tailored properties.

Basic Information

Product Name	4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenylethynyl-Trimethylsilane
CAS No.	870238-65-6
Molecular Formula	C19H29BO2Si
Molecular Weight	328.33 g/mol
Synonyms	2-[4-[(Trimethylsilyl)ethynyl]phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-((Trimethylsilyl)ethynyl)benzeneboronic acid pinacol ester; 4-Ethynylphenylboronic acid pinacol ester, trimethylsilyl-protected; (4-((Trimethylsilyl)ethynyl)phenyl)boronic acid pinacol ester; TMS-EthynylphenylBPin; CAS 870238-65-6
EINECS	Contact for details

Quality Control

Our 4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenylethynyl-Trimethylsilane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR, HPLC, and GC, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.