Description

1,3,2-Dioxaborolane, 4,4,5,5-Tetramethyl-2-[2-(4-Nitrophenoxy)Phenyl]- is a specialized organoboron compound featuring a pinacol boronic ester group and a nitrophenoxy-substituted aromatic system. This unique structure makes it a valuable high-purity synthetic intermediate for constructing complex molecules in advanced research and development. It is primarily needed by pharmaceutical, agrochemical, and materials science industries for applications in catalysis, cross-coupling reactions, and the synthesis of functional organic materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key boron reagent for forming carbon-carbon bonds in the synthesis of complex biaryl structures for active pharmaceutical ingredients (APIs) and advanced materials.
• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of drug candidates, particularly those requiring nitrophenoxy or biphenyl motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where its specific aromatic framework is incorporated.
• Organic Light-Emitting Diode (OLED) Materials: Acts as a precursor in the development of electron-transport or emissive layer materials for display and lighting technologies.
• Ligand Synthesis for Catalysis: Employed in the preparation of sophisticated ligands for transition metal catalysts used in asymmetric synthesis.
• Polymer & Functional Material Research: Utilized to introduce boronic ester functional groups into polymers for sensors, self-healing materials, or responsive hydrogels.

Basic Information

Product Name	1,3,2-Dioxaborolane, 4,4,5,5-Tetramethyl-2-[2-(4-Nitrophenoxy)Phenyl]-
CAS No.	870221-30-0
Molecular Formula	C18H20BNO5
Molecular Weight	341.17 g/mol
Synonyms	2-[2-(4-Nitrophenoxy)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; [2-(4-Nitrophenoxy)phenyl]boronic acid pinacol ester; 2-(4-Nitrophenoxy)phenylboronic acid pinacol ester; 4,4,5,5-Tetramethyl-2-[2-(4-nitrophenoxy)phenyl]-1,3,2-dioxaborolane; (2-(4-Nitrophenoxy)phenyl)boronic acid pinacol ester; PINACOL 2-(4-NITROPHENOXY)PHENYLBORONATE
EINECS	Contact for details

Quality Control

Our 1,3,2-Dioxaborolane, 4,4,5,5-Tetramethyl-2-[2-(4-Nitrophenoxy)Phenyl]- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed specifications are provided and can be tailored to meet specific research or cGMP guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.