Description

Benzoic Acid, 2-Bromo-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-, Methyl Ester is a high-value, multi-functional organic building block that combines a bromo-substituted benzoate core with a pinacol boronate ester group. This compound matters for its critical role in modern synthetic chemistry, enabling precise carbon-carbon bond formation via cross-coupling reactions like the Suzuki-Miyaura reaction. Pharmaceutical, agrochemical, and advanced materials researchers need it for the efficient synthesis of complex molecules, drug candidates, and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly in oncology and CNS research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science: Precursor for creating functional polymers, liquid crystals, and organic electronic materials (OLEDs, OFETs).
• Cross-Coupling Reactions: Essential reagent in Suzuki-Miyaura coupling for constructing biaryl and conjugated systems.
• Chemical Research & Development: Versatile synthon for medicinal chemistry, process chemistry, and exploring new synthetic methodologies.
• Ligand and Catalyst Development: Used to create novel bidentate ligands and organometallic catalysts.

Basic Information

Product Name	Benzoic Acid, 2-Bromo-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-, Methyl Ester
CAS No.	870195-96-3
Molecular Formula	C15H20BBrO4
Molecular Weight	355.04 g/mol
Synonyms	Methyl 2-Bromo-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate; 2-Bromo-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic Acid Methyl Ester; 2-Bromo-5-(pinacolatoboryl)benzoic Acid Methyl Ester; Methyl 2-Bromo-5-(pinacolatoboryl)benzoate; 870195-96-3; Boronic acid, B-[2-bromo-5-(methoxycarbonyl)phenyl]-, pinacol ester; (2-Bromo-5-methoxycarbonylphenyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our Benzoic Acid, 2-Bromo-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-, Methyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR (1H, 13C, 11B), and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our commitment to quality supports your R&D and scale-up processes with reliable, high-purity material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (GC)	≥96.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.