Description

Pyridine-4-Boronic Acid, Neopentyl Ester is a high-value organoboron building block, specifically a protected boronic acid ester, designed for advanced synthetic chemistry. This compound is crucial for enabling efficient and selective cross-coupling reactions, such as the Suzuki-Miyaura reaction, which are foundational to modern pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent for constructing biaryl and heterobiaryl scaffolds prevalent in active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides through targeted cross-coupling methodologies.
• Materials Science & OLED Development: Serves as a building block for creating organic electronic materials, including ligands for metal-organic frameworks (MOFs) and emissive layers in OLEDs.
• Academic & Industrial R&D: Essential for methodological development in organic synthesis and catalysis studies.
• Ligand Synthesis for Catalysis: Used to prepare sophisticated pyridine-containing ligands for transition metal catalysis.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and bioconjugates for studying biological systems.

Basic Information

Product Name	Pyridine-4-Boronic Acid, Neopentyl Ester
CAS No.	869901-52-0
Molecular Formula	C11H16BNO2
Molecular Weight	205.06 g/mol
Synonyms	4-(Neopentyloxy)-4-pyridinylborane; 4-(Neopentyloxy)pyridine-4-boronic Acid; 4-Pyridinylboronic Acid Neopentyl Ester; 4-(Neopentyloxy)pyridine-4-ylboronic Acid; Neopentyl 4-Pyridylboronate; 4-(Neopentyloxy)-4-pyridinylboronic Acid; 4-(Neopentyloxy)pyridine-4-ylborane; 4-Pyridylboronic Acid Neopentyl Ester
EINECS	Contact for details

Quality Control

Our Pyridine-4-Boronic Acid, Neopentyl Ester is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity, typically ≥95% (by HPLC/NMR). Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality management system is designed to meet the stringent requirements of advanced R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.