Description

2-Amino-N-(2,2,2-trifluoroethyl)benzamide is a specialized aromatic amide building block featuring a trifluoroethyl substituent, offering unique electronic and steric properties for advanced chemical synthesis. This compound is valued for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where the trifluoromethyl group is prized for enhancing metabolic stability and lipophilicity. It is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoroethyl moiety can improve biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of functional polymers and organic electronic materials that require fluorine-containing aromatic units.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects and scale-up processes.

Basic Information

Product Name	2-Amino-N-(2,2,2-trifluoroethyl)benzamide
CAS No.	869629-11-8
Molecular Formula	C9H9F3N2O
Molecular Weight	218.18 g/mol
Synonyms	N-(2,2,2-Trifluoroethyl)anthranilamide; 2-Amino-N-(2,2,2-trifluoroethyl)benzamide; Benzamide, 2-amino-N-(2,2,2-trifluoroethyl)-; Anthranilamide, N-(2,2,2-trifluoroethyl)-; 869629-11-8; 2-Amino-benzoic acid (2,2,2-trifluoro-ethyl)-amide
EINECS	Contact for details

Quality Control

Our 2-Amino-N-(2,2,2-trifluoroethyl)benzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment and are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids, strong bases, and oxidizing agents. The material is moisture-sensitive; ensure the container is kept tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.