Description

3-(4-Fluorophenyl)-5-Methylisoxazole-4-Carboxaldehyde is a high-purity fluorinated isoxazole derivative, a crucial advanced pharmaceutical intermediate (API) and versatile building block in organic synthesis. Its core value lies in its unique molecular scaffold, which is integral to the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate a fluorinated heterocyclic moiety into their target molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-inflammatory agents, and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, where the fluorophenyl-isoxazole structure can enhance biological activity and environmental stability.
• Organic Synthesis Building Block: Serves as a versatile precursor for further chemical transformations, including the synthesis of more complex heterocycles, Schiff bases, and other functionalized derivatives.
• Material Science Research: Investigated as a monomer or precursor for the development of specialty polymers, liquid crystals, and organic electronic materials due to its rigid, planar structure.
• Chemical Biology & Proteomics: Utilized as a reactive handle or probe in bioconjugation chemistry and the development of chemical tools for studying biological systems.

Basic Information

Product Name	3-(4-Fluorophenyl)-5-Methylisoxazole-4-Carboxaldehyde
CAS No.	869496-66-2
Molecular Formula	C11H8FNO2
Molecular Weight	205.19 g/mol
Synonyms	4-Fluoro-α-(5-methyl-4-isoxazolyl)benzeneacetaldehyde; 5-Methyl-3-(4-fluorophenyl)isoxazole-4-carboxaldehyde; 3-(p-Fluorophenyl)-5-methyl-4-isoxazolecarboxaldehyde; 4-Formyl-5-methyl-3-(4-fluorophenyl)isoxazole; 869496-66-2; 3-(4-Fluorophenyl)-5-methyl-1,2-oxazole-4-carbaldehyde
EINECS	Contact for details

Quality Control

Our 3-(4-Fluorophenyl)-5-Methylisoxazole-4-Carboxaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.