Description

5-Bromo-6-Chloro-2,2-Difluorobenzo[D][1,3]Dioxole is a high-purity, multi-halogenated benzodioxole derivative serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in its unique molecular scaffold, which enables the construction of complex molecules, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific halogenated motifs into their target structures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and insecticides, where the difluorobenzodioxole moiety can enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for developing novel fluorinated polymers, liquid crystals, and electronic materials with specific optical or electronic properties.
• Organic Synthesis & Method Development: A valuable substrate for chemists developing new catalytic cross-coupling reactions, halogen-exchange processes, and other transformative synthetic methodologies.
• Chemical Reference Standard: Utilized as a high-purity analytical standard in quality control laboratories for method development and impurity profiling in related chemical processes.

Basic Information

Product Name	5-Bromo-6-Chloro-2,2-Difluorobenzo[D][1,3]Dioxole
CAS No.	869188-52-3
Molecular Formula	C7H2BrClF2O2
Molecular Weight	279.45 g/mol
Synonyms	5-Bromo-6-chloro-2,2-difluoro-1,3-benzodioxole; 2,2-Difluoro-5-bromo-6-chloro-1,3-benzodioxole; 1,3-Benzodioxole, 5-bromo-6-chloro-2,2-difluoro-; 869188-52-3; 5-Br-6-Cl-2,2-F2-benzodioxole
EINECS	Contact for details

Quality Control

Our 5-Bromo-6-Chloro-2,2-Difluorobenzo[D][1,3]Dioxole is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Purity (GC)	≥97.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.