Description

Diisopropyl 3-Hydroxycyclobutane-1,1-Dicarboxylate is a high-purity, functionalized cyclobutane derivative that serves as a versatile and valuable synthetic intermediate. Its unique structure, featuring both ester and hydroxyl groups on a strained four-membered ring, makes it a critical building block for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and advanced materials sectors for applications in medicinal chemistry and polymer science.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Advanced Material Synthesis: Building block for creating specialty polymers and monomers with tailored thermal and mechanical properties.
• Agrochemical Research: Used in the development of new generation herbicides and plant growth regulators with novel modes of action.
• Ligand and Catalyst Development: Serves as a scaffold for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and cellular pathways.
• Academic & Industrial R&D: Fundamental research reagent for exploring new organic reactions and ring-strain chemistry.

Basic Information

Product Name	Diisopropyl 3-Hydroxycyclobutane-1,1-Dicarboxylate
CAS No.	869109-31-9
Molecular Formula	C12H20O5
Molecular Weight	244.28 g/mol
Synonyms	3-Hydroxycyclobutane-1,1-dicarboxylic acid diisopropyl ester; Diisopropyl 3-hydroxycyclobutane-1,1-dicarboxylate; 1,1-Bis(isopropoxycarbonyl)-3-hydroxycyclobutane; 3-Hydroxy-1,1-cyclobutanedicarboxylic Acid Diisopropyl Ester; 3-Hydroxycyclobutane-1,1-dicarboxylate Diisopropyl Ester; Diisopropyl 3-Hydroxy-1,1-cyclobutanedicarboxylate
EINECS	Contact for details

Quality Control

Our Diisopropyl 3-Hydroxycyclobutane-1,1-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high standards, such as cGMP development and advanced material research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.