Description

2-Cyanopyridine-3-Boronic Acid Neopentyl Glycol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex heterocyclic scaffolds. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly those containing bipyridine or related heterocyclic systems.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with complex pyridine-based structures.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in catalysis and coordination chemistry.
• Material Science Research: Building block for organic electronic materials, such as those used in OLEDs and conductive polymers.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological processes.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.

Basic Information

Product Name	2-Cyanopyridine-3-Boronic Acid Neopentyl Glycol Ester
CAS No.	868944-75-6
Molecular Formula	C13H17BN2O2
Molecular Weight	244.10 g/mol
Synonyms	2-Cyano-3-pyridinylboronic acid neopentyl glycol ester; (2-Cyanopyridin-3-yl)boronic acid neopentyl ester; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)picolinonitrile; 2-Cyano-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-Cyanopyridine-3-boronic acid pinacol ester (common misnomer); Picolinonitrile, 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; Boronic acid, B-(2-cyano-3-pyridinyl)-, 1,1-dimethylethylene ester
EINECS	Contact for details

Quality Control

Our 2-Cyanopyridine-3-Boronic Acid Neopentyl Glycol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and scale-up applications. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.