Description

2-Trifluoromethyl-5-Pyridineboric Acid is a high-value organoboron building block, specifically a pyridine-substituted boronic acid derivative. This compound is essential for modern synthetic chemistry, enabling the efficient construction of complex molecules through cross-coupling reactions. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key reagent in Suzuki-Miyaura cross-coupling reactions for constructing biaryl and heterobiaryl scaffolds found in drug candidates.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging the trifluoromethyl group's metabolic stability.
• Material Science Research: Serves as a building block for creating novel organic electronic materials, ligands for catalysts, and metal-organic frameworks (MOFs).
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and inhibitors for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for clients.

Basic Information

Product Name	2-Trifluoromethyl-5-Pyridineboric Acid
CAS No.	868662-36-6
Molecular Formula	C7H5BF3NO2
Molecular Weight	190.93 g/mol
Synonyms	(5-Pyridinyl)boronic acid, 2-(trifluoromethyl)-; 2-(Trifluoromethyl)pyridine-5-boronic acid; 5-Borono-2-(trifluoromethyl)pyridine; 2-Trifluoromethyl-5-pyridylboronic acid; (2-Trifluoromethyl-5-pyridinyl)boronic acid; 2-CF3-5-Pyridineboronic Acid; 2-CF3-Pyridine-5-Boronic Acid
EINECS	Contact for details

Quality Control

Our 2-Trifluoromethyl-5-Pyridineboric Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay (by HPLC), identity confirmation (by 1H NMR and IR), and impurity profiles. Our quality management system is designed to meet the stringent requirements of research and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.