Description

2-(5-Bromo-2-Methoxyphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a crucial building block in modern synthetic chemistry. Its value lies in its role as a key intermediate for Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing complex biaryl or heterobiaryl motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific aryl-aryl linkages.
• Material Science: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for constructing complex molecular architectures via palladium-catalyzed cross-coupling.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands and organometallic catalysts.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke fine chemicals.

Basic Information

Product Name	2-(5-Bromo-2-Methoxyphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	868629-78-1
Molecular Formula	C13H18BBrO3
Molecular Weight	313.00 g/mol
Synonyms	5-Bromo-2-methoxyphenylboronic acid pinacol ester; (5-Bromo-2-methoxyphenyl)boronic acid pinacol ester; 2-Methoxy-5-bromophenylboronic acid pinacol ester; Pinacol (5-bromo-2-methoxyphenyl)boronate; 5-Bromo-2-methoxybenzeneboronic acid pinacol ester; 868629-78-1; B-2-Methoxy-5-bromophenylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Every batch of our 2-(5-Bromo-2-Methoxyphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured and tested under a strict quality management system. We ensure high purity and batch-to-batch consistency through advanced analytical techniques including HPLC, GC, and NMR. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to maintain product integrity and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.