Description

Ethyl 1-[(4-Fluorophenyl)Methyl]-2-Methylpyrrole-3-Carboxylate is a high-purity, fluorinated pyrrole derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its specific substitution pattern enables precise molecular design. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to innovate and scale new molecular entities.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the development of next-generation pesticides and herbicides, leveraging the fluorophenyl moiety for enhanced biological activity and stability.
• Material Science Research: Serves as a precursor for functionalized polymers or organic electronic materials due to its pyrrole core.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds or molecular probes for biochemical and pharmacological studies.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	Ethyl 1-[(4-Fluorophenyl)Methyl]-2-Methylpyrrole-3-Carboxylate
CAS No.	868551-47-7
Molecular Formula	C15H16FNO2
Molecular Weight	261.29 g/mol
Synonyms	1-[(4-Fluorobenzyl)]-2-methyl-1H-pyrrole-3-carboxylic acid ethyl ester; Ethyl 1-(4-fluorobenzyl)-2-methyl-1H-pyrrole-3-carboxylate; 1H-Pyrrole-3-carboxylic acid, 1-[(4-fluorophenyl)methyl]-2-methyl-, ethyl ester; 868551-47-7; 1-(4-Fluorobenzyl)-2-methylpyrrole-3-carboxylic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our Ethyl 1-[(4-Fluorophenyl)Methyl]-2-Methylpyrrole-3-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.