Description

1,3-Dimethyl 5-(Trifluoromethyl)Benzene-1,3-Dicarboxylate is a high-value fluorinated aromatic building block, serving as a critical intermediate in advanced organic synthesis. Its core value lies in the strategic incorporation of the trifluoromethyl group, which imparts desirable properties like enhanced metabolic stability and lipophilicity to target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in oncology, CNS, and antiviral drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the CF3 group improves efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials and organic light-emitting diodes.
• Functional Polymer Monomer: Incorporated into specialty polymers to enhance chemical resistance, thermal stability, and surface properties.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions, esterifications, and nucleophilic substitutions to construct complex fluorinated architectures.
• Material Science Research: Employed in R&D for developing novel fluorinated coatings, additives, and advanced materials.

Basic Information

Product Name	1,3-Dimethyl 5-(Trifluoromethyl)Benzene-1,3-Dicarboxylate
CAS No.	868286-79-7
Molecular Formula	C11H9F3O4
Molecular Weight	262.18 g/mol
Synonyms	Dimethyl 5-(Trifluoromethyl)isophthalate; 5-(Trifluoromethyl)isophthalic Acid Dimethyl Ester; 1,3-Bis(methoxycarbonyl)-5-(trifluoromethyl)benzene; Isophthalic Acid, 5-(Trifluoromethyl)-, Dimethyl Ester; Dimethyl 5-Trifluoromethylisophthalate; NSC 405124
EINECS	Contact for details

Quality Control

Our 1,3-Dimethyl 5-(Trifluoromethyl)Benzene-1,3-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.